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  • Catalog NO.:A927927
  • CAS No. : 2137047-43-7
  • Molecular Formula:C16H12F5N3O
  • Molecular Weight: 357.28
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Product Details

CAS Number 2137047-43-7 Appearance Yellow powder
Catalog Number A927927 MDL Number MFCD31619260
Molecular Formula C16H12F5N3O Molecular Weight 357.28
Boiling Point Melting Point
Flash Point Density
Synonyms Pyrazolo[1,5-a]pyrimidine, 3-(2,3-difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)-
Storage Condition Store in a tightly closed container,in a cool and dry place


GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302;H315;H319;H335 Class
Precautionary Statements P261;P305+P351+P338 Packing Group


FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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Pyrazolo[1,5-a]pyrimidine, 3-(2,3-difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)-