CHIR99021 trihydrochloride

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For R&D use only.

Catalog NO.：A904010
CAS No. : 1782235-14-6
Molecular Formula：C₂₂H₂₁Cl₅N₈
Molecular Weight： 574.72

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Product Details

CAS Number	1782235-14-6	Appearance
Catalog Number	A904010	MDL Number
Molecular Formula	C₂₂H₂₁Cl₅N₈	Molecular Weight	574.72
Boiling Point		Melting Point
Flash Point		Density
Synonyms	6-((2-((4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile trichloride
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

CHIR-99021, also known as CT99021, is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. CHIR-99021 inhibits GSK-3 with IC50 at 7 nM. In a series of carcinoma cell lines, the IC50 of CHIR99021 for proliferation is about 10μM.

252917-06-9 (free base)

1782235-14-6 (3HCl)

2109414-84-6 (2HCl)

1797989-42-4 (HCl)

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