BMS345541
- Catalog NO.:A872511
- CAS No. : 445430-58-0
- Molecular Formula:C14H17N5
- Molecular Weight: 255.32
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 445430-58-0 | Appearance | |
Catalog Number | A872511 | MDL Number | MFCD18089812 |
Molecular Formula | C14H17N5 | Molecular Weight | 255.32 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | N-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine;BMS-345541 | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302 | Class | |
Precautionary Statements | P280-P305+P351+P338 | Packing Group |
Description
BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0.3 and 4.0 μM for IKKβ and IKKα respectively). It attenuates LPS-induced cytokine production in vitro and blocks NFκB dependent transcription in mice. BMS 345541 also suppresses joint destruction in a mouse model of arthritis. |