BIIB021 (mesylate)

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For R&D use only.

Catalog NO.：A903995
CAS No. : 1225041-97-3
Molecular Formula：C₁₅H₁₉ClN₆O₄S
Molecular Weight： 414.87

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Product Details

CAS Number	1225041-97-3	Appearance
Catalog Number	A903995	MDL Number
Molecular Formula	C₁₅H₁₉ClN₆O₄S	Molecular Weight	414.87
Boiling Point		Melting Point
Flash Point		Density
Synonyms	BIIB 021 mesylate;CNF 2024 mesylate;CNF-2024 mesylate; 6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine methanesulfonate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

BIIB021, also known as CNF2024, is an orally active, purine-scaffold, small-molecule inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90 inhibitor CNF2024 specifically blocks active HSP90, inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival; this may result in the inhibition of cellular proliferation in susceptible tumor cell populations.

1225041-97-3 (mesylate)

848695-25-0 (free base)

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