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[CAS No.1624306-20-2] A1256987 甲磺酸吉泊达星二水合物 98%
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(R)-2-((4-(((3,4-二氢-2H-吡喃并[2,3-c]吡啶-6-基)甲基)氨基)哌啶-1-基)甲基)-1,2-二氢3H,8H-2a,5,8a-三氮杂苊烯-3,8-二酮
Reason:活性分子抑制剂
Gepotidacin hydrochloride
Reason:活性分子抑制剂
产品详情 [1624306-20-2]

Gepotidacin, also known as GSK-2140944, is a potent Type II DNA topoisomerase inhibitor. Gepotidacin is a novel antibacterial drug candidate. Gepotidacin Demonstrates Absence of Fluoroquinolone-Like Arthropathy in Juvenile Rats. Gepotidacin is efficacious in a nonhuman primate model of pneumonic plague. When tested against Gram-negative (n = 333) and Gram-positive (n = 225) anaerobes by agar dilution, gepotidacin inhibited 90% of isolates at concentrations of 4 and 2 μg/mL, respectively.

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